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  • Oslo Sports Trauma Research Center - 134 - An analysis of the quality of cartilage repair studies
    Start date 2004 End date 2008 Print Descriptions Proper use of sound scientific methodology in clinical trials is paramount to the validity of the results and of particular relevance when new treatments are being implemented Methods In this project we have performed extensive literature searches in the fields of cartilage treatment techniques and treatment of posterior cruciate ligament tears All retrieved trials have been critically appraised using standardized methods in

    Original URL path: http://www.klokavskade.no/en/Project/134---An-analysis-of-the-quality-of-cartilage-repair-studies/ (2015-09-15)
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  • Oslo Sports Trauma Research Center - 171 - Risk of injury on artificial turf in Nordic football
    difficult climatic conditions A Swedish study found no evidence of increased risk of injury on third generation artificial turf compared to playing on natural grass in professional football Ekstrand et al 2006 The aim of the study was to compare the risk of acute injury on third generation artificial turf to natural grass in male professional football Methods A prospective injury registration in the male Norwegian professional league N 14

    Original URL path: http://www.klokavskade.no/en/Project/171---Risk-of-injury-on-artificial-turf-in-Nordic-football/ (2015-09-15)
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  • Oslo Sports Trauma Research Center - 118 - Natural course of cartilage injuries in the knee
    underlying the cartilage osteochondritis dissecans Surgical treatment of cartilage injuries is still controversial because we do not know if the results of treatment are better than the natural course In addition we do not know whether any of the surgical treatment options are better than the others In 1999 a six months registration of all knee arthroscopies at the Central Hospital of Akershus Martina Hansen Hospital and Ullevål University Hospital was performed These three hospitals serve approximately 500 000 inhabitants A scoring system developed by the International Cartilage Research Society ICRS was used The study showed that 11 of the knees that underwent knee arthroscopy had a full thickness focal cartilage injury About half of these injuries 6 had a area of more than 2 square centimeters European football team handball and skiing were the predominating activities that led to injury The results from this primary registration are accepted for publication Årøen et al We now plan to perform a five year follow up study fall 2004 of the patients in this study with a confirmed full thickness cartilage injury of more than 2cm2 and a matched control group the control group will be matched in relation to age gender

    Original URL path: http://www.klokavskade.no/en/Project/118---Natural-course-of-cartilage-injuries-in-the-knee/ (2015-09-15)
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  • Oslo Sports Trauma Research Center - 146 - Performance aspects of an injury prevention program: A 10-week intervention in adolescent female football players
    effect of such a program on performance is not known Aim To investigate the effect of the 11 on performance after a 10 week training period Design Randomized controlled clinical trail Methods 34 female adolescent football players were randomly assigned to either a training n 18 or a control group n 16 The 11 is a 15 min program consisting of ten exercises for core stability lower extremity strength balance

    Original URL path: http://www.klokavskade.no/en/Project/146---Performance-aspects-of-an-injury-prevention-program-A-10-week-intervention-in-adolescent-female-football-players/ (2015-09-15)
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  • Oslo Sports Trauma Research Center - 125 - Traumatic brain injuries in football due to minor head trauma a prospective clinical study
    baseline testing prior to the 2004 season The computerised test battery showed excellent reproducibility for the reaction time measures and these measures were therefore recommended as the test s primary outcome variables However a small but significant practise effect was found and a dual baseline testing with rejection of the first test is advised to minimise this effect Paper II In this paper we found no effect of previous concussions and self reported heading exposure on the neuropsychological performance in Norwegian professional football players The results were based on the neuropsychological test results for the 271 players who were tested at baseline 2004 The vast majority 96 1 of these football players revealed in addition no evidence of cognitive impairments when compared to normative data Paper III This paper discussed the results from the analysis of the S100B samples In addition to the head impacts and the controls that were recruited from the regular league matches three teams N 48 performed one high intensity exercise session without heading and one low intensity exercise with heading exercises The serum levels of S100B were measured before the first training and within one and twelve hours after each of the two training sessions Of the total of 228 head impacts registered during the two football seasons 65 28 5 impacts were followed up with blood samples one hour after the impact and 40 17 5 the following morning Both football training and football matches led to a transient increase in serum S100B up to the cut off level for what is considered as borderline pathological values Minor head impacts did not cause an additional increase in the S100B level beyond what was measured after a regular match All serum S100B values were below what is measured for hospital admitted minor head trauma patients

    Original URL path: http://www.klokavskade.no/en/Project/125---Traumatic-brain-injuries-in-football-due-to-minor-head-trauma-a-prospective-clinical-study-/ (2015-09-15)
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  • Oslo Sports Trauma Research Center - 133 - Cartilage injuries. The use of stem cells in joint resurfacing
    the subchondral bone plate do show self repair but the repair cartilage consists mostly of fibrous cartilage One out of ten patients seeking medical help due to knee pain has a significant cartilage injury Approximately 50 of these have a lesion that would benefit from and is suitable for surgical treatment Development of new surgical strategies has introduced the use of ex vivo expanded chondrocytes implanted as a cell suspension into the defect under a periosteal flap The procedure requires cartilage to be harvested from a low weight bearing part of joint thereby creating a small but potentially harmful defect in the cartilage Results have been promising but few well organized randomised studies have been performed Aims and methods 1 Chondrocytes differentiate when cultured adhering to plastic in a monolayer Recent results suggest that for chondrocytes to fully redifferentiate a three dimensional matrix scaffold is needed We will try to culture chondrocytes in different scaffold materials and determine which scaffold is best in making chondrocytes redifferentiate Scaffolds made of hyaluronic acid alginate or collagen are the most likely candidates 2 Chondrocytes are of mesenchymal lineage We culture stem cells of mesenchymal lineage derived from bone marrow synovial or adipose tissue

    Original URL path: http://www.klokavskade.no/en/Project/133---Cartilage-injuries-The-use-of-stem-cells-in-joint-resurfacing-/ (2015-09-15)
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  • Oslo Sports Trauma Research Center - 118 - Autologous chondrocyte transplantation versus autologous transplantation of mesenchymal stem cells in the repair of cartilage injuries in the rabbit patella
    knee In the microfracture technique several holes are made in the subchondral bone plate The belief is that bone marrow cells migrates to the injury area and contributes to the formation of a fiber cartilage to replace the original cartilage In mosaic plasty plugs consisting of cartilage and underlying bone are taken from less weight bearing areas of the joint and used to replace the injured cartilage In periosteal transplantation the cartilage injury is covered by a periosteal flap Periosteum contains mesenchymal stem cells that are thought to be the source of cartilage formation in this method In autologous chondrocyte transplantation a small piece of cartilage is taken from a less weight bearing area of the joint cultured and the number of cells are multiplied After two or three weeks the Joint is opened the defect is covered by periosteal flap and the cells are injected under the flap There are few studies that compared the different methods and we do not know if any of them are better than the others A theoretical disadvantage of the use of chondrocytes is that these cells are mature cells that are past the stadium of cell differentiation and cell division In autologous chondrocyte transplantation these mature cells are stimulated to cell division mesenchymal stem cells are the mother cell of bone cartilage fat and muscle Theoretically mesenchymal stem cells may be better than cartilage cells in forming cartilage be cause they still have a natural potential for cell differentiation and cell division Some animal studies have been performed using mesenchymal stem cells with the same technique as in autologous chondrocyte transplantation In deep defects into the subchondral bone the use of mesenchymal stem cells induced bone formation in the areas lacking bone and cartilage formation in the areas lacking cartilage We have

    Original URL path: http://www.klokavskade.no/en/Project/118---Autologous-chondrocyte-transplantation-versus-autologous-transplantation-of-mesenchymal-stem-cells-in-the-repair-of-cartilage-injuries-in-the-rabbit-patella/ (2015-09-15)
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  • Oslo Sports Trauma Research Center - 045 - Prevention of football injuries: an intervention study
    found that the players using ankle orthosis or the group that followed a proprioceptive programme had significantly less ankle sprains than the controls Surve et al 1994 showed a reduction of the number of ankle injuries using ankle orthosis Caraffa et al 1996 found that the number of torned anterior cruciate ligaments among football players was reduced by 70 after preventive proprioceptive training In a study of female high school students by Heidt et al 2000 seven weeks of preseason conditioning significantly reduced the total number of injuries Whereas Søderman et al 2000 found that no significant effect was observed on the rate of lower extremity injuries in female players after the introduction of a program with 10 15 minutes of daily balance board training Junge et al 2002 in a study of male youth amateur players found that significantly fewer injuries occurred in the intervention group who had participated in a prevention program Previous injury is the most dominating risk factor for injuries in soccer Arnason et al Am J Sports Med In press 2003 Tropp et al 1985 Ankle and knee sprains and hamstring and groin strains are the 4 most dominating injuries and stand for more than 50 of all soccer injuries Arnason et al Am J Sports Med In press 2003 The aim of this intervention study is to reduce the number of soccer injuries through specific pre season training of previously injured players We will randomize into two groups of 300 players each One group will work as a control group while in the intervention group all players with a history of previous injury in ankle knee groin or hamstring will receive a special training program and the equipment needed during 10 weeks in the pre season and maintenance throughout the season Screening of previous

    Original URL path: http://www.klokavskade.no/en/Project/045---Prevention-of-football-injuries-an-intervention-study-/ (2015-09-15)
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